- Is an uncommon, genetic condition that causes the liver to retain alpha-1 antitrypsin
- Can be diagnosed by a doctor’s physical exam and blood test. Liver biopsy or ultrasound may be ordered
- Can present and cause liver problems in infants, children or adults
- Liver may be gradually damaged and scarred and may progress to cirrhosis, liver failure
- Transplant is curative
Signs & Symptoms:
- In babies, symptoms include jaundice (eyes and skin turning yellow) swelling of the abdomen, and poor growth
- Older children and adults may experience the above and may report feeling weak and tired
- Most children and adults with alpha-1 have no symptoms of liver disease at all
Treatment and Follow-up:
Although there is no cure for Alpha-1, there are ways to prevent or reduce health problems related to Alpha-1. People with Alpha-1 should do the following:
- get hepatitis A and B vaccinations
- get regular exams by a doctor
- get regular medical tests as suggested by their doctors, such as blood tests and liver ultrasound or X-ray tests – for example, liver CT (CAT) scans
- stay away from tobacco smoke and heavy air pollution
- avoid drinking alcohol
- eat a balanced diet and maintain a healthy weight
- speak to your doctor before using any herbal, vitamin or other therapies
